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<p> </p> <p><span style="font-size: 18pt;"><strong>Brief introduction</strong></span></p> <p><span style="font-size: 12pt;">In this article we will present some guidelines that must be taken into account when knowing how to interpret results about DNA tests between alleged siblings or half-siblings.</span></p> <p> </p> <figure class="image"><img src="/cms/uploads/editor/20220916022518_siblings-interpretation-dna-results.jpg" alt="brothers dna results" width="439" height="247" /> <figcaption> <p style="text-align: left;"><em><span style="font-size: 10pt;">The interpretation of the results will give conclusive results to you and your siblings.</span></em></p> </figcaption> </figure> <p> </p> <p> </p> <p><span style="font-size: 12pt;">To be able to identify the results, you need to know a little about it, and to take into account some scientific data, which are not difficult to understand.</span></p> <p><span style="font-size: 12pt;">Many times, we receive the preliminary report - the results of a DNA test - and we do not know how to recognize the results of it. So, here we bring you a little information about this genetic test, and so that you know how to read the solution of the study that you and your brother have successfully carried out.</span></p> <p> </p> <p><em><span style="font-size: 12pt;">See also: <a title="Make DNA International distance" href="https://homednapaternitykit.com/article/how-to-carry-out-a-dna-test-if-i-live-abroad-20" target="_blank" rel="noopener">How to carry out a DNA test if I live abroad?</a></span></em></p> <p> </p> <p><span style="font-size: 18pt;"><strong>Data to interpret a DNA test between siblings</strong></span></p> <p><span style="font-size: 12pt;">In order to better understand the details of the sibling test results, it is important to emphasize that you are familiar with the terms for proper understanding, and the science behind how a sibling DNA test works.</span></p> <p> </p> <figure class="image"><img src="/cms/uploads/editor/20220916002420_percentages-and-probabilities.jpg" alt="calculator to perform the calculation of the sibling rates" width="519" height="346" /> <figcaption> <p><em><span style="font-size: 10pt;">The calculation is very simple, because it consists of two values only</span></em></p> </figcaption> </figure> <p> </p> <p><span style="font-size: 12pt;">In this test, our laboratory generates a DNA profile with specific genetic markers (also known as short tandem repeats or <strong>STRs</strong>) at a set of known locations (<strong>loci or singular, locus</strong>) in your DNA.</span></p> <p><span style="font-size: 12pt;">At each DNA locus, you can find 2 genetic variants - known as <strong>alleles</strong> - which are each inherited, one by the mother and one by the father.3</span></p> <p> </p> <figure class="image"><img src="/cms/uploads/editor/20220916002641_alleles-DNA-test.jpg" alt="dna test human dna image" width="499" height="281" /> <figcaption> <p><em><span style="font-size: 10pt;">Human DNA seen through a special microscope.</span></em></p> </figcaption> </figure> <p> </p> <div id="tw-target-text-container" class="tw-ta-container F0azHf tw-nfl" tabindex="0"> <p id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><em><span class="Y2IQFc" lang="en" style="font-size: 12pt;">Read More: <a title="Access to our Labs to send saliva samples" href="https://homednapaternitykit.com/article/ways-to-access-the-laboratory-to-send-dna-samples-19" target="_blank" rel="noopener">Ways to access the laboratory to send DNA samples. </a></span></em></p> </div> <div id="tw-target-rmn-container" class="tw-target-rmn tw-ta-container F0azHf tw-nfl"> <pre id="tw-target-rmn" class="tw-data-placeholder tw-text-small tw-ta" dir="ltr" data-placeholder=""></pre> </div> <div> <div> <div data-cviv="false" data-ved="2ahUKEwi_woGN3pf6AhUhq5UCHYs8A30Qz_AEegQIAxAP"> <div> </div> </div> </div> </div> <p><span style="font-size: 12pt;">The laboratory technique that is used to amplify the DNA study is called <strong>polymerase chain reaction (PCR)</strong>. In a sibling DNA test, PCR analysis is used to determine which alleles are specific, which ones they have at each DNA locus, also known as the genetic profile. If two individuals share at least one allele in common, it means that a match already exists.</span></p> <p><span style="font-size: 12pt;">True siblings or half-siblings need to match on some alleles. This is because siblings don't always inherit the same DNA markers from their parents; Therefore, if this were the opposite case, all the brothers would be practically identical.</span></p> <p> </p> <figure class="image"><img src="/cms/uploads/editor/20220916002938_identical-sisters.jpg" alt="dna identical sisters photo" width="423" height="619" /> <figcaption> <p><em><span style="font-size: 10pt;">The sibling index establishes whether two siblings of the same <br />or opposite sex are full siblings or half siblings.</span></em></p> </figcaption> </figure> <p> </p> <p> </p> <div id="tw-container" class="" data-cp="1" data-is-ver="false" data-nnttsvi="1" data-sbsl="ru,uk" data-sm="1" data-ssbp="false" data-sugg-time="500" data-sugg-url="https://clients1.google.com/complete/search" data-uilc="es-419"> <div id="tw-ob" class="tw-src-ltr"> <div class="oSioSc"> <div id="tw-target"> <p id="tw-target-text-container" tabindex="0"></p> <p dir="ltr" data-placeholder="Traducción"><span style="font-size: 18pt;"><strong><span lang="en">Interpreting your results</span></strong></span></p> <p><span style="font-size: 12pt;">As soon as you have the report of the results in your hands, here you will find a graph that represents the DNA profiles of each person who has participated in the analysis.</span></p> <div id="tw-container" class="" data-cp="1" data-is-ver="false" data-nnttsvi="1" data-sbsl="ru,uk" data-sm="1" data-ssbp="false" data-sugg-time="500" data-sugg-url="https://clients1.google.com/complete/search" data-uilc="es-419"> <div id="tw-ob" class="tw-src-ltr"> <div class="oSioSc"> <div id="tw-target"> <div id="kAz1tf" class="g9WsWb"> <div id="tw-target-text-container" class="tw-ta-container F0azHf tw-nfl" tabindex="0"> <p id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><span lang="en"><br /></span><span lang="en">You </span><span class="Y2IQFc" lang="en"><em><span style="font-size: 12pt;">may also be interested in this: <a title="Grandparent Test DNA" href="https://homednapaternitykit.com/article/grandparent-test-useful-information-about-it-17" target="_blank" rel="noopener">Make your Grandparent Test DNA. Cheap and easy to do.</a></span></em></span></p> <p dir="ltr" data-placeholder="Traducción"> </p> <p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><span style="font-size: 12pt;">The numbers in the <strong>Putative Sibling 1</strong> and <strong>Putative Sibling 2</strong> columns are values</span> <span style="font-size: 12pt;">that represent the two alleles that you and your putative sibling received from your parents at the corresponding genetic marker. You can have two identical alleles on a marker (for example the number <strong>14</strong>), or you can have two different alleles (for example the numbers <strong>13,14</strong>). If the same number is present in both columns, that means you <strong>match</strong> the corresponding genetic marker of your suspected sibling.</span></p> </div> </div> </div> </div> </div> </div> <p> </p> <table style="border-collapse: collapse; width: 68.6488%; height: 117px;" border="2"><caption><em><span style="font-size: 10pt;">Full and Half Sisterhood Rate Table</span></em></caption> <tbody> <tr> <td style="width: 16.3566%; text-align: center;"><strong>DNA Locus</strong></td> <td style="width: 23.6675%; text-align: center;"><strong>Putative Sibling One</strong></td> <td style="width: 23.6675%; text-align: center;"><strong>Putative Sibling One</strong></td> <td style="width: 18.3392%; text-align: center;"><strong>Sibling Index</strong><br /><strong>(Full)</strong></td> <td style="width: 18.0914%; text-align: center;"><strong>Sibling Index</strong><br /><strong>(Half)</strong></td> </tr> <tr> <td style="width: 16.3566%; text-align: center;">D8S1145</td> <td style="width: 23.6675%; text-align: center;">13,14</td> <td style="width: 23.6675%; text-align: center;">14</td> <td style="width: 18.3392%; text-align: center;">1.32</td> <td style="width: 18.0914%; text-align: center;">1.57</td> </tr> <tr> <td style="width: 16.3566%; text-align: center;">D24S54</td> <td style="width: 23.6675%; text-align: center;">28,30</td> <td style="width: 23.6675%; text-align: center;">28,30</td> <td style="width: 18.3392%; text-align: center;">4.25</td> <td style="width: 18.0914%; text-align: center;">1.72</td> </tr> </tbody> </table> <p> </p> <p><span style="font-size: 12pt;">The first column, labeled <strong>DNA Locus</strong>, lists those genetic markers that have been tested for that sibling DNA test (<strong>genetic marker example: D8S1145</strong>).</span></p> <p><span style="font-size: 12pt;">The final two columns, both <strong>Sib Rate (Full)</strong> and <strong>Sib Rate (Half)</strong>, represent the statistical strength of a single match at the corresponding genetic marker. These values are calculated based on the type of match, which is normally expected as positive results for true pairs, between full siblings, and both half siblings.</span></p> <p> </p> <p> </p> <p><span style="font-size: 18pt;"><strong>Guild Composite Index</strong></span></p> <p> </p> <table style="border-collapse: collapse; width: 68.8243%; height: 131px;" border="2"><caption><em><span style="font-size: 10pt;">Sibship Index Table</span></em></caption> <tbody> <tr style="height: 19.566px;"> <td style="width: 11.5288%; height: 19.566px; line-height: 1; border-style: solid; text-align: center;"><strong>Sibship Index</strong></td> <td style="width: 88.4708%; height: 19.566px; line-height: 1; border-style: solid; text-align: center;"><strong>Explanation</strong></td> </tr> <tr style="height: 22.3785px;"> <td style="width: 11.5288%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><strong><span style="font-size: 12pt;">0.01</span></strong></td> <td style="width: 88.4708%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><span style="font-size: 12pt;">The individuals are 100% more likely not to be true siblings than siblings.</span></td> </tr> <tr style="height: 22.3785px;"> <td style="width: 11.5288%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><strong><span style="font-size: 12pt;">10</span></strong></td> <td style="width: 88.4708%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><span style="font-size: 12pt;">The individuals are 10% more likely to be true siblings than not siblings.</span></td> </tr> <tr style="height: 22.3785px;"> <td style="width: 11.5288%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><strong><span style="font-size: 12pt;">100</span></strong></td> <td style="width: 88.4708%; height: 22.3785px; line-height: 1; border-style: solid; text-align: center;"><span style="font-size: 12pt;">The individuals are 100% more likely to be true siblings than not siblings.</span></td> </tr> </tbody> </table> <p> </p> <p><span style="font-size: 12pt;">A <strong>higher sibling index</strong> (greater than 1.0) corresponds to a higher probability of kinship. The higher that value is above 1.0, the greater the probability that the two individuals are related as <strong>true siblings</strong>.</span></p> <p> <span class="Y2IQFc" lang="en" style="font-size: 12pt;">Order your brotherhood test now and get rid of your doubts about whether your brother is a full brother, a half brother, or if he does not have any type of genetic relationship: </span><a style="font-size: 12pt;" title="Order any test DNA" href="https://homednapaternitykit.com/order_service/1" target="_blank" rel="noopener">Order now!</a></p> <p> </p> <figure class="image"><img src="/cms/uploads/editor/20220916003256_half-brothers.jpg" alt="half siblings with sibling index results" width="435" height="290" /> <figcaption> <p><em><span style="font-size: 10pt;">In this way, you can find out if your alleged brother <br />is 100 percent compatible with you.</span></em></p> </figcaption> </figure> <p> </p> <p><span style="font-size: 12pt;">If, on the other hand, a brotherhood index (less than 1.0) corresponds to a lower probability of kinship. <strong>The lower this sibling index</strong> is less than 1.0, the <strong>lower the probability</strong> that the two individuals are related as identical blood siblings.</span></p> <p> </p> <p><span style="font-size: 18pt;"><strong>So how do we know if we are half siblings or full siblings?</strong></span></p> <p><span style="font-size: 12pt;">The division that exists to calculate the percentage of brotherhood that exists between two presumed brothers is the following:</span></p> <p> </p> <div id="tw-container" class="" data-cp="1" data-is-ver="false" data-nnttsvi="1" data-sbsl="ru,uk" data-sm="1" data-ssbp="false" data-sugg-time="500" data-sugg-url="https://clients1.google.com/complete/search" data-uilc="es-419"> <div id="tw-ob" class="tw-src-ltr"> <div class="oSioSc"> <div id="tw-target"> <div id="kAz1tf" class="g9WsWb"> <div id="tw-target-text-container" class="tw-ta-container F0azHf tw-nfl" tabindex="0"> <p id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><span style="font-size: 12pt;"><em><span class="Y2IQFc" lang="en">Maybe this will help you: <a title="Make your Home DNA kit." href="https://homednapaternitykit.com/article/at-home-make-your-own-kit-for-a-dna-test-step-by-step-from-scratch-14" target="_blank" rel="noopener">Make your own Home DNA Kit. Cheap, easy to do and quickly. Step by step.</a></span></em></span></p> </div> <div id="tw-target-rmn-container" class="tw-target-rmn tw-ta-container F0azHf tw-nfl"> <pre id="tw-target-rmn" class="tw-data-placeholder tw-text-small tw-ta" dir="ltr" data-placeholder=""></pre> </div> <div class="iYB33c"> <div> <div data-cviv="false" data-ved="2ahUKEwi_woGN3pf6AhUhq5UCHYs8A30Qz_AEegQIAxAP"> </div> </div> <div id="tw-tmenu" class="tw-menu"><span id="tw-cpy-btn" class="tw-menu-btn" tabindex="0" title="Copiar" role="button" data-action-target="target" aria-label="Copiar texto" data-ved="2ahUKEwi_woGN3pf6AhUhq5UCHYs8A30Q69UBegQIAxAS"></span><span id="tw-spkr-button" class="tw-menu-btn za3ale" tabindex="0" role="button" data-action-target="target" data-sttse="true" aria-label="Texto a voz" data-ved="2ahUKEwi_woGN3pf6AhUhq5UCHYs8A30Q8DR6BAgDEBQ"></span></div> </div> </div> </div> </div> </div> <div id="tw-images"></div> <div> </div> </div> <p><strong><span style="font-size: 12pt;">You must</span></strong><span style="font-size: 12pt;"> divide </span><strong><span style="font-size: 12pt;">the </span></strong><span style="font-size: 12pt;"><strong><span class="wysiwyg-color-blue130">Combined Sibship Index </span></strong></span><strong><span style="font-size: 12pt;">divided (full) by the </span><span style="font-size: 12pt;">Combined Sibship Index (half).</span></strong></p> <p><span style="font-size: 12pt;"><strong>In such a way, based on an example</strong>: if a pair of brothers has a complete brotherhood index of 1.2 and an average brotherhood index of 40, it means that both are 33.3 times more likely to be half brothers than full brothers. (in numeric text mode this is 40 ÷ 1.2 = 33.33 percent chance).</span></p> <p> </p> <p><span style="font-size: 12pt;"><img style="display: block; margin-left: auto; margin-right: auto;" src="/cms/uploads/editor/20220916010201_division.jpg" alt="" width="547" height="80" /></span></p> <p> </p> <div id="tw-container" class="" data-cp="1" data-is-ver="false" data-nnttsvi="1" data-sbsl="ru,uk" data-sm="1" data-ssbp="false" data-sugg-time="500" data-sugg-url="https://clients1.google.com/complete/search" data-uilc="es-419"> <div id="tw-ob" class="tw-src-ltr"> <div class="oSioSc"> <div id="tw-target"> <div id="kAz1tf" class="g9WsWb"> <div id="tw-target-text-container" class="tw-ta-container F0azHf tw-nfl" tabindex="0"> <p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><span class="Y2IQFc" lang="en" style="font-size: 12pt;">This is how you can calculate and interpret your <strong>sibling DNA test results</strong>. </span></p> <p dir="ltr" data-placeholder="Traducción"> </p> <p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Traducción"><span style="font-size: 12pt;">Carry out your DNA tests and <strong>obtain results with a probability of 99.99999% of proven effectiveness</strong>. Contact us to order a DNA test between siblings or half siblings, by </span><strong style="font-size: 12pt;">WhatsApp: +1-877-219-4485</strong></p> </div> </div> </div> </div> </div> </div> <figure class="image"><img src="/cms/uploads/editor/20220916003516_contact-us-by-whatsapp.jpg" alt="send us a message by whatsapp" width="521" height="347" /> <figcaption> <p><em><span style="font-size: 10pt;">Our operators will assist you with quality service and good disposition.</span></em></p> </figcaption> </figure> <p dir="ltr" data-placeholder="Traducción"> </p> <p class="g9WsWb" style="text-align: left;"><span style="font-size: 12pt;">We offer customer service in three different languages: <strong>Spanish, French and English</strong>. We are here to help you resolve your concerns.</span><span style="font-size: 12pt;">If you want to place the order directly, you can do it through this link: <a title="Order Test" href="https://homednapaternitykit.com/order_service/1" target="_blank" rel="noopener">Order Now</a></span></p> <p id="kAz1tf" class="g9WsWb" style="text-align: left;"></p> </div> </div> </div> </div>
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Information on how to interpret DNA test results between alleged siblings or half-siblings, through probability and quotient calculation.
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